Абдурахмонова, Маржона and Хонов, Алавиддин (2025) ПАТОФИЗИОЛОГИЧЕСКАЯ ТРАНСФОРМАЦИЯ НИШИ КОСТНОГО МОЗГА ПРИ ХРОНИЧЕСКОМ ЛИМФОЛЕЙКОЗЕ. INTERNATIONAL CONFERENCE ON MEDICINE, SCIENCE, AND EDUCATION; Vol. 2 No. 10 (2025): INTERNATIONAL CONFERENCE ON MEDICINE, SCIENCE, AND EDUCATION; 235-239.
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Abstract
The article examines in detail the pathophysiological mechanisms of bone marrow microenvironment transformation in chronic lymphocytic leukemia (CLL). The concept of "niche dependency" of tumor cells is substantiated. Changes in mesenchymal stem cells, the vascular component, and the immune landscape of the niche are analyzed. The role of exosomal transport and hypoxia in the development of drug resistance is considered.
| Item Type: | Article |
|---|---|
| Additional Information: | Imported from International Conference on Medicine, Science, and Education |
| SWORD Depositor: | Admin User |
| Depositing User: | Admin User |
| Date Deposited: | 26 Sep 2026 22:27 |
| Last Modified: | 26 Sep 2026 22:27 |
| URI: | https://universalpublishings.uz/id/eprint/12848 |
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