Qo‘ziyev, Otabek and Yusupov, Akmal (2026) IMMUNIZATSIYA QILINGAN TAJRIBA QUYON MODELIDA BRUTSELLYOZ TA’SIRIDA TALOQDAGI PATOMORFOLOGIK O‘ZGARISHLAR. South Aral Region Medical Journal; Vol. 2 No. 3/1 (2026): JANUBIY OROL BOʼYI TIBBIYOT JURNALI; 145-151.
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Abstract
Immunizatsiya qilingan tajriba quyon modelida Brucella abortus 19 shtammining tirik vaksinasi ta’sirida taloqdagi patomorfologik o‘zgarishlar o‘rganildi. Tadqiqotda vazni 3,0–3,5 kg bo‘lgan 12 ta quyon 4 guruhga taqsimlanib, turli sxemalar asosida (Freynd adyuvanti bilan va sof vaksina) 4 marta immunizatsiya qilindi. Taloq to‘qimalarining gistologik tekshiruvida (gematoksilin-eozin bo‘yash) limfoid to‘qimalarning giperplaziyasi, limfo-gistiotsitar infiltratsiya, mikrogranulyomalar hosil bo‘lishi, makrofaglar faolligining oshishi hamda retikuloendotelial tizim hujayralarining proliferatsiyasi kuzatildi. Aniqlangan morfologik o‘zgarishlar Brucella abortus 19 shtammining immunogenligini hamda brutsellyoz infeksiyasi patogenezida taloqning muhim rol o‘ynashini ko‘rsatadi
| Item Type: | Article |
|---|---|
| Additional Information: | Imported from South Aral Region Medical Journal |
| SWORD Depositor: | Admin User |
| Depositing User: | Admin User |
| Date Deposited: | 27 Sep 2026 22:18 |
| Last Modified: | 27 Sep 2026 22:18 |
| URI: | https://universalpublishings.uz/id/eprint/15105 |
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